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HomeDosing & AdministrationDosing &
Administration5 Through 11 Years of AgePresentationDosing Chart12 Years of Age and OlderPresentationDosing ChartResourcesResourcesLinks & SupportOrderingReimbursement HubCDC Child Immunization SchedulePfizer Customer ServiceShipment SupportVaccine FinderMaterialsDropdownLabelLinkLinkLinkLink
IndicationPrescribing InformationPatient InformationPatient SiteOrder on Pfizer PrimeApproved Vaccine Option 12+ Years of Age
Order from Pfizer Prime

Stock your office with COMIRNATY to help protect 
eligible individuals.

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The 2025-2026 Formula of COMIRNATY®
(COVID-19 Vaccine, mRNA) is now available in two age-appropriate dosing presentations1:
Dosing for pediatric patients 5 through 11 years of age
 View 5-11 Years Dosing LoadingDosing for pediatric patients 12 years of age and older View 12+ Years Dosing Loading
Your recommendation matters2
Discussing COVID-19 vaccination with parents and caregivers of eligible individuals can be an important first step in helping to protect them against COVID-19.
Ordering available through Pfizer Prime*
Orders for 2025-2026 formula COVID-19 vaccines by BioNTech and Pfizer can be placed by eligible healthcare professionals directly with Pfizer through Pfizer Prime online or by calling 1-800-533-4535. Button Loading

Eligible healthcare providers can order COVID-19 vaccines directly from Pfizer. If preferred, orders may be placed with your facility’s wholesaler.

COVID-19=coronavirus disease 2019.
References:COMIRNATY® (COVID-19 Vaccine, mRNA). Prescribing Information. BioNTech Manufacturing GmbH and Pfizer Inc.; August 27, 2025.For health care providers. US Department of Health and Human Services. Updated February 20, 2025. Accessed August 13, 2025. https://www.hhs.gov/risk-less-do-more/for-health-care-providers/index.html
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BioNTech Manufacturing GmbH
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55131 Mainz, Germany
Marketing Authorization Holder
Manufactured by
Pfizer Inc.
New York, NY 10001

COVID-19 vaccines from BioNTech and Pfizer, which are based on BioNTech proprietary mRNA technology, were developed by both BioNTech and Pfizer.

To report an adverse event, please call 1-800-438-1985

Pfizer for Professionals 1-800-505-4426

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You are now leaving PfizerProYou are now leaving a Pfizer-operated website. Links to all outside sites are provided as a resource to our visitors. Pfizer accepts no responsibility for the content of sites that are not owned and operated by Pfizer.PP-MCL-USA-0367
INDICATIONCOMIRNATY® (COVID-19 Vaccine, mRNA) is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID‑19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2).

COMIRNATY is approved for use in individuals who are:
• 65 years of age and older, or
• 5 years through 64 years of age with at least one underlying condition that puts them at high risk for severe outcomes from COVID-19.
Important Safety InformationDo not administer COMIRNATY® (COVID-19 Vaccine, mRNA) to individuals with known history of a severe allergic reaction (e.g., anaphylaxis) to any component of COMIRNATY or to individuals who had a severe allergic reaction (e.g., anaphylaxis) following a previous dose of a Pfizer-BioNTech COVID-19 vaccine.Management of Acute Allergic ReactionsAppropriate medical treatment must be immediately available to manage potential anaphylactic reactions following administration of COMIRNATY.Myocarditis and PericarditisPostmarketing data from use of authorized or approved mRNA COVID-19 vaccines, including COMIRNATY, have demonstrated increased risks of myocarditis and pericarditis, with onset of symptoms typically in the first week following vaccination. The observed risk has been highest in males 12 years through 24 years of age.SyncopeSyncope (fainting) may occur in association with administration of injectable vaccines, including COMIRNATY. Procedures should be in place to avoid injury from fainting.Altered ImmunocompetenceImmunocompromised persons, including individuals receiving immunosuppressant therapy, may have a diminished immune response to COMIRNATY.Limitation of Vaccine EffectivenessCOMIRNATY may not protect all vaccine recipients.Adverse ReactionsMost commonly reported adverse reactions after a dose:
  • 12 years of age and older (≥10%) were pain at the injection site (up to 90.5%), fatigue (up to 77.5%), headache (up to 75.5%), chills (up to 49.2%), muscle pain (up to 45.5%), joint pain (up to 27.5%), fever (up to 24.3%), injection site swelling (up to 11.8%), and injection site redness (up to 10.4%).
     
  • 5 years through 11 years of age (≥5%) were pain at the injection site (up to 83.8%), fatigue (up to 51.9%), headache (up to 38.4%), injection site redness (up to 25.9%), injection site swelling (up to 20%), muscle pain (up to 18.1%), chills (up to 13.3%), fever (up to 7.8%), and joint pain (up to 7.6%).
To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or https://www.pfizersafetyreporting.com or VAERS at 1-800-822-7967 or https://vaers.hhs.gov Please click for COMIRNATY Full Prescribing Information and Patient Information.IndicationCOMIRNATY is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID‑19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2).COMIRNATY is approved for use in individuals who are:
  • 65 years of age and older, or
  • 5 years through 64 years of age with at least one underlying condition that puts them at high risk for severe outcomes from COVID-19.